Toxins, like chemicals from pollution and smoking, can prematurely age your skin. They may contribute to wrinkles, age spots, and uneven color. For example, people who smoke often discover that the chemicals in cigarettes damage the skin's elasticity, leading to sagging or wrinkles.

A skin lesion refers to any skin area that has different characteristics from the surrounding skin, including color, shape, size, and texture. Skin lesions are very common and often appear as a result of a localized damage to the skin, like sunburns or contact dermatitis.